Lab News…
May 2023
Congratulations to Xingyu and Sean for completing their M.S. degrees! They have been outstanding lab members and we are lucky to have them both continue on in our lab. We look forward to their continued success!
April 2023
Bardan receives the Shirley Schmones Wallach Research Scholar Award for his research on MSCs in tissue maintenance and regeneration! Congratulations!
March 2023
Katia receives the Goldwater Scholarship for her work on MSC adipogenesis! Congratulations!
February 2023
We continue to grow with Anna, a graduate student from Tandon School of Engineering, and Sahil, a medical student from NY College of Podiatric Medicine joining the lab. Welcome aboard!
January 2023
Sally joins the lab as a senior research scientist. We are happy to have her as part of our team and look forward to the future!
February 2022
Veronica presents at the Musculoskeletal Research Center Work in Progress Meeting and Edgar gives a seminar at the Regenerative Medicine Research Seminar Series
Two new members join the lab - Xingyu from Tandon NYU as graduate researcher and Bardan as a student researcher.
December 2021
The lab is growing! Tenzin joins as a Fulbright graduate researcher and Katia as an undergraduate researcher.
October 2021
Edgar presents at the Musculoskeletal Research Center Work in Progress Meeting and Vikrant gives a seminar at the Regenerative Medicine Research Seminar Series
Also, two new great additions to the lab! Ling joins as a visiting medical student and Danielle joins as undergraduate researcher!
September 2021
Edgar and Vikrant sort cells for the first time on the east coast!
July 2021
Veronica and Vikrant present at the Musculoskeletal Research Center Work in Progress Meeting.
June 2021
Mike presents in the Regenerative Medicine Research Seminar Series
May 2021
Edgar arrives to the lab as a Senior Scientist/Laboratory Coordinator and brings a chill California vibe to the lab.
November 2020
Mike gives a Translational Research in Progress (TRIP) seminar.
October 2020
Vikrant transfers from HSS in NYC and joins the lab as a postdoctoral fellow.
September 2020
Ana joins the lab as an undergraduate researcher with a focus on programming pipelines for the processing of data from single cell sequencing.
August 2020
The laboratory reopens!
July 2020
Veronica joins the lab in the midst of the pandemic as a postdoctoral fellow.
March 2020
The Wosczyna Laboratory opens but the Covid-19 pandemic causes a pause in operations.
Selected Publications
Targeting microRNA-mediated gene repression limits adipogenic conversion of skeletal muscle mesenchymal stromal cells
Michael N. Wosczyna, Edgar E. Perez Carbajal, Mark W. Wagner, Silvana Paredes, Colin T. Konishi, Ling Liu, Theodore T. Wang,Rachel A. Walsh, Qiang Gan, Christapher S. Morrissey, and Thomas A. Rando
Cell Stem Cell. 2021, July 01; 28, 1323–1334
DOI: https://doi.org/10.1016/j.stem.2021.04.008
A single-cell transcriptomic atlas characterizes ageing tissues in the mouse
Tabula Muris Consortium
Nature. 2020 Jul; 583(7817): 590-595.
Mesenchymal Stromal Cells Are Required for Regeneration and Homeostatic Maintenance of Skeletal Muscle
Wosczyna, Michael N; Konishi, Colin T; Perez Carbajal, Edgar E; Wang, Theodore T; Walsh, Rachel A; Gan, Qiang; Wagner, Mark W; Rando, Thomas A
Cell Reports. 2019, May 14; 27(7):2029-2035.e5
DOI: 10.1016/j.celrep.2019.04.074
Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris
Tabula Muris Consortium
Nature. 2018, October 03; 562: 367-372
DOI: https://doi.org/10.1038/s41586-018-0590-4
Bioengineered Viral Platform for Intramuscular Passive Vaccine Delivery to Human Skeletal Muscle
Paulk, Nicole K; Pekrun, Katja; Charville, Gregory W; Maguire-Nguyen, Katie; Wosczyna, Michael N; Xu, Jianpeng; Zhang, Yue; Lisowski, Leszek; Yoo, Bryan; Vilches-Moure, Jose G; Lee, Gordon K; Shrager, Joseph B; Rando, Thomas A...
Molecular Therapy. Methods & Clinical Development. 2018, Sep 21; 10:144-155
A Muscle Stem Cell Support Group: Coordinated Cellular Responses in Muscle Regeneration
Wosczyna, Michael N; Rando, Thomas A
Developmental Cell. 2018, July 16; 46(2):135-143
Multipotent progenitors resident in the skeletal muscle interstitium exhibit robust BMP-dependent osteogenic activity and mediate heterotopic ossification
Wosczyna, Michael N; Biswas, Arpita A; Cogswell, Catherine A; Goldhamer, David J
Journal Of Bone & Mineral Research. 2012 May; 27(5):1004-17
DOI: 10.1002/jbmr.1562
Identification of progenitor cells that contribute to heterotopic skeletogenesis
Lounev, Vitali Y; Ramachandran, Rageshree; Wosczyna, Michael N; Yamamoto, Masakazu; Maidment, Andrew D A; Shore, Eileen M; Glaser, David L; Goldhamer, David J; Kaplan, Frederick S
Journal Of Bone & Joint Surgery (American Volume). 2009 Mar 01; 91(3):652-63
DOI: 10.2106/JBJS.H.01177